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Mount Sinai scientists earn  million to elucidate novel causes of food allergies and atopic dermatitis

Mount Sinai scientists earn $12 million to elucidate novel causes of food allergies and atopic dermatitis

Mount Sinai scientists earn  million to elucidate novel causes of food allergies and atopic dermatitis

Mount Sinai researchers were awarded $12 million over five years by the National Institutes of Health to establish a center to uncover new causes and drivers of food allergies and atopic dermatitis.

The Systems Biology of Early Atopy (SunBEAm) Center for Analytical and Bioinformatics aims to advance our understanding of allergy pathogenesis. The center applies systems biology to identify early markers of risk for food allergy and atopic dermatitis (also known as eczema), and the biological pathways underlying these common conditions. increase. A multicenter prenatal cohort of 2,500 children.

Food allergy and atopic dermatitis are complex diseases, affecting approximately 8% and 20% of children, respectively. Food allergy often precedes atopic dermatitis, suggesting common risk factors and overlapping pathobiology.

Individuals with food allergies are at daily risk of potentially life-threatening conditions such as urticaria, dyspnea, and/or anaphylaxis after ingestion of sensitized food antigens. And for people who suffer from atopic dermatitis, they live with chronically inflamed skin that can cover a significant portion of their body.

Supinda Bunyavanich, MD, MPH, MPhil, Mount Sinai Professor of Allergy and Systems Biology and Principal Investigator of the Center

“This funding will allow us to create a center of great impact in allergy research. It can help us identify new knowledge about food allergies and ultimately help us to improve the prevention, diagnosis and clinical management of food allergies and atopic dermatitis,” said Dr Bunjavanich. increase.

The SunBEAm Analytical and Bioinformatics Center includes researchers from the University of North Carolina at Mount Sinai, Johns Hopkins and Chapel Hill, Northwestern University, and National Jewish Health. The SunBEAm Birth Cohort is a collaboration of researchers from 12 locations across the United States who are enrolling families participating in this cohort study that tracks parents and children from prenatal through the child’s third birthday. SunBEAm is supported by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health (grant number 1UM1AI173380-01) and led by the Food Allergy Research Consortium.

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Mount Sinai Health System

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